Simons Foundation support for converting whole-brain Drosophila imaging data from a Simons Collaboration on Plasticity and the Aging Brain lab to NWB
The Simons Collaboration on Plasticity and the Aging Brain (SCPAB), which the Simons Foundation launched in 2020, studies mechanisms of resilience and functional maintenance in the aging brain across many model systems. Through SCPAB, the Simons Foundation funded CatalystNeuro to help labs in the collaboration convert their data to Neurodata Without Borders (NWB) and publish it on the DANDI Archive.
The work covered volumetric two-photon calcium imaging of the whole brain in Drosophila walking on an air-suspended ball. We wrote an imaging extractor for the lab’s NIfTI volumes and Bruker metadata and added FicTrac ball tracking and atlas-registered processed volumes. The data are published as Dandiset 000727, with 18 NWB files from 9 flies, about 0.6 TB.
NWB conversions under this project
1 labs
Thomas Clandinin
Stanford University
Developed NWB conversion tools for the Clandinin lab's whole-brain imaging data in Drosophila, featuring volumetric two-photon calcium imaging while flies walked on an air-suspended ball. The conversion includes custom interfaces for the lab's NIfTI imaging files and Bruker metadata, processed brain volumes registered to an atlas, and FicTrac ball tracking.